That's now my setup at work, we are moving to a new office in 2 months, really looking forward to have a window - and working in an as our boss says 'sexy' office.
I am struggling a little bit with my now more sophisticated multi monitor setup. Using Mac OS as main OS, and Windows virtualized, and applications which use more than one screen is a little bit difficult. Now every screen uses its own 'Space' and that's so far OK, but some things do not really work perfect: for example windows stay on the same screen like they should - and do not forget their screen they are attached to - but the size is automatically changed all the time on the left screen. Also a problem with using Spaces is, that using more than one screen with an application is sometimes not possible, and sometimes also positions are not remembered.
In general the multi monitor support of Mac OS is not that bad at all, but could be better! I have to try some tools, someone uses BetterTouchTool or similar? I would like to have support without tools and only use the functions of the OS though, but in that case a little helper could be good!