I've had mixed profiles on a keyboard before. It's not too big a deal, as long as all your A-Z and number keys are the same profile. I would not recommend replacing only some of the keys in that areas, though I (and others)have done so with no great harm. You will notice a difference, however.
So, your DAS has OEM profile keycaps (If I remember correctly). You would want to replace them with keycaps of the same profile (More OEM keycaps). If not, it would be uneven.
If you just wanted to replace some modifiers, then I imagine it wouldn't be too bad.
In practice, I don't find SP profile to be too different than Cherry profile, my SP Moogle kit (replacing the modifiers) fits rather well with my cherry keycaps.
But both cherry and SP are noticeably shorter than OEM profile.