I own a LH DSI- got it because I thought the ergonomics would be nice, but the muscle memory for the arrow keys was too great and I kept reaching for keys that weren't there. Didnt give it enough time, but it was annoying enough that I ditched it pretty quickly. So for me, southpaw layout sounds like best of both worlds.
Instead, I've got a Nyquist (could use a let's split) that I'll be converting one half (5*6) into a combo numpad and arrows and pgup, etc so I can have that on the left when I want it.
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