First post outside of the new member forum. I've historically preferred full-size layouts but I've used a TKL for a few years with the Novatouch. Like others, I like that I can keep the keyboard closer to center aligned when touch-typing without having to reach as far to the mouse. A few weeks back, I ended up buying a mechanical numpad off of Amazon for data entry, but having it on the right made me miss the ergonomics of the TKL.
More recently, I planned to buy an 1800 layout in the form of the Leopold FC980M, but I instead opted for the FC660M which I received today. It's probably as small as I'm willing to go though, I can't give up the arrow cluster. I'm also trying my numpad out on the left side, which while very awkward at first, has some theoretical advantages in certain applications. For example, number entry in spreadsheets would allow me to keep the left hand on the numpad while my right hand can stay on the mouse or arrow keys. I also like the inherent modularity of being able to move the numpad out of the way when I don't need it.
The one thing for me that really exaggerated the annoyance of mouse-reaching was getting used to the trackpoint on my thinkpads. I ended up buying an external thinkpad keyboard a few months back just for that reason, but I ended up missing having mechanical keys. The Tex Yoda might be nice for me if it had arrow keys and was a little less expensive. The Tex Kodachi is just too rich for my blood right now. For now, the smaller Leopold is ideal for my needs and budget.