This is commonly referred to as north and south facing LEDs(north being top and south being bottom). The issue that some have noticed, at least from my reading, is that north facing has issues with GMK/Cherry cap travel, meaning switches can't bottom out fully, on the smaller profile caps like row 3.
As for tactility, it wouldn't have a noticeable effect unless you constantly hit on saw the bottom of a cap and when you rotate the tactile bumps are on the opposite side of the switch now so it would behave slightly(and I mean very, very slightly) differetly, but not to the point you can say they are different levels of tactility(unless of course the switch in question has massive amounts of wobble in the stem).