Agreed. The first two weeks for me were very frustrating, as I make frequent use of the brace and bracket keys, as well as the tilde. Now the row feels pretty awesome, and the arrow key placement is good as well. I hit these keys no problem. As per suggestions of others on this forum, I did swap my UP arrow with the DOWN arrow, as it felt more natural, and reduced a lot of cursor movement mistakes.
My biggest gripe so far is that due to some of the thumb key mappings changed, I accidentally hit home and end once in a while. I need to find a better place for them. They're close to my backspace key, which gets constant use.
How long have you been typing on the Advantage, Icarium?
Agree with boli: Give it time. I used to hit them accidentally all the time in the beginning as well, but now I think it's pretty good to have the keys nearby :-)