These are great as auxillary keyboards (I use a KVM for my main keyboard, but have 2 ML4100s connected so I can type on either PC quickly without hassle.)
They are even good for alternative layouts, since the keys are all the same height.
Unfortunately, the \ key is slightly wider than the # key on the UK version, so I couldn't quite get a perfect Colemak layout. If I was bothered, I suppose it could be filed down to make the swap possible.
This would be a good way to learn an alternative layout if you want to leave the keyboard you type on as Qwerty or blank. The ML4100 would act as a visual guide when you need to check a location. As a bonus if you need to type anything critical like a password, or type one-handed when you use the 'phone, you can go to the ML4100.
Having typed on them for a bit recently, I have to say the switches are slightly 'balky'. Not dreadful, but clearly a step below MX switches.