You should expect a week or so of awkwardness. I doubt you'll be able to use it at work right away. Personally, it took a few weeks to get to a point where I could use my atreus at work, and even then I wasn't all that efficient. That being said, it's like riding a bike -- once you figure it out you'll have that with you for a while.
Personally, I ended up moving away from ortho after a while. It does make sense for the way in which we type, but I didn't have the patience to break years of muscle memory and rebuild. But it's all about finding your preference, so you could like it a whole lot more than I did.