I went just the opposite direction ... pinky keys have browns, not-homerow browns have 50gr springs, and the thumb keys have 100gr clears so they can properly slow my thumbs down when I mash keys.
But for the 1x keys around the 2x keys ... sure, I could see making those reds. I've never worked with the acrylic plate; can you open them up without desoldering? Just put a switch slider in for a week, see what you think.