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geekhack Community => Other Geeky Stuff => Topic started by: tp4tissue on Sat, 13 April 2024, 20:34:50

Title: Ozempic
Post by: tp4tissue on Sat, 13 April 2024, 20:34:50
So, Tp4 be watching the documentary, and it' like,  the guy straight up says, 

"It takes away the joy of eating, nothing tastes the same."

You read that and it's like, ok something is horribly wrong, if "THAT" is the cure people are paying for.

(https://i.imgur.com/HmeSYmM.jpg)

So how it works is, it's a chemical that goes in the brain, and down-regulates the pathway which regulates hunger/ desire to eat/ satiation.  It's the #1 selling diet craze/fad for a few years now. People even shell out for bootleg from compound pharmacies, and based on talking to some people (in Tp4's bad people circles), Tp4 suspects they're using illegally imported Indian precursors.
Title: Re: Ozempic
Post by: Rhienfo on Sun, 14 April 2024, 05:29:52
I mean ozempic is a great innovation in both type 2 diabetes treatments and weight loss. A lot of countries have a lot of people who are obese and ozempic will help greatly with that. The only real concerns that I have is that once you are on ozempic, it's hard to get off it without gaining massive amounts of weight afterwards because it's the thing keeping your appetite down, which means that you aren't really practicing good eating/healthy practices and how it's being advertised, making it so that massive amounts of people buying it, to the point where there is shortages and also us healthcare system bad as well.

This video is pretty good about ozempic I'd recommend watching it.

Title: Re: Ozempic
Post by: noisyturtle on Sun, 14 April 2024, 05:35:18
Yeah, I asked my doc about it and she quoted me $1.2K monthly

Rich person weight loss only, I guess :(
Title: Re: Ozempic
Post by: fohat.digs on Sun, 14 April 2024, 08:37:26
I have a friend who is an excellent cook and loves cooking and eating, but suffers from diabetes.

He has been using it for nearly a year and says that it is very effective at keeping his diabetes at bay. He has also lost considerable weight, and yes, says that he gets very hungry when he skips it.

But I worry that it is sapping his energy and enjoyment of life ....
Title: Re: Ozempic
Post by: tp4tissue on Sun, 14 April 2024, 12:01:02
The brain acclimates to semaglutide the same way it would to any exogenous chemical. Over time you'd need more. The documentary already mentions that even within a year or 2, the dosage has to go up.

But what happens if someone uses this stuff for say 20 years, and suddenly comes off,  are we going to see suicides like zoloft (ssri)/ antidepressants ?

This is not a fix for anything, hesitate to even call it a good patch.

[attachimg=1]
Title: Re: Ozempic
Post by: tp4tissue on Sun, 14 April 2024, 17:37:00
Another big issue, stomach paralysis. So the increase in the hormone release slows stomach emptying, and some users end up with stomach paralysis,  and there are reports that the problem continued even AFTER they stopped taking the medication.

(https://i.imgur.com/hVaXskJ.gif)
Title: Re: Ozempic
Post by: Rob27shred on Mon, 15 April 2024, 08:00:14
Quote from: tp4tissue on Sun, 14 April 2024, 12:01:02
The brain acclimates to semaglutide the same way it would to any exogenous chemical. Over time you'd need more. The documentary already mentions that even within a year or 2, the dosage has to go up.

But what happens if someone uses this stuff for say 20 years, and suddenly comes off,  are we going to see suicides like zoloft (ssri)/ antidepressants ?

This is not a fix for anything, hesitate to even call it a good patch.

(Attachment Link)

There is no free lunch with anything in excess & taking any type of drug (for treatment or recreation) leads to an excess of whatever it mimics or forces our bodies to overproduce. Anyone who has any experience with drugs can tell you this stuff for weight loss is a terrible ideal. I get using it for diabetes or any other life threating condition cause the positives outweigh the negatives in that situation. For any other reason though, you're just asking for trouble.
Title: Re: Ozempic
Post by: OrinNYC on Fri, 13 December 2024, 18:33:15
I took it - lost a bunch of weight but i also maintained my diet and the gym after i stopped!
Title: Re: Ozempic
Post by: pixelpusher on Sat, 14 December 2024, 13:39:35
Quote from: tp4tissue on Sat, 13 April 2024, 20:34:50
So, Tp4 be watching the documentary, and it' like,  the guy straight up says, 

"It takes away the joy of eating, nothing tastes the same."

You read that and it's like, ok something is horribly wrong, if "THAT" is the cure people are paying for.

Show Image
(https://i.imgur.com/HmeSYmM.jpg)


So how it works is, it's a chemical that goes in the brain, and down-regulates the pathway which regulates hunger/ desire to eat/ satiation.  It's the #1 selling diet craze/fad for a few years now. People even shell out for bootleg from compound pharmacies, and based on talking to some people (in Tp4's bad people circles), Tp4 suspects they're using illegally imported Indian precursors.

I've been on terzepatide for 4 months.  I'm now down to the weight I was as a young adult entering college.  I slowly increased my dosage each month and then decreased when my appetite dropped too low.  It doesn't take the joy out of eating for me at all.  I just don't think about food as much.  The body's "crave" mechanism is curbed.  I actually have to remind myself to eat if I'm busy doing other things.  I've always eaten fairly healthy, so I don't really eat anything different on the shots but I do eat less.  And because of that, it promotes better eating.  Do I want to eat a cookie that tastes delicious and find myself "full," knowing that I just ate empty calories, or do I want to eat health complex carbs and protein?  Easy choice!

I find myself much more satisfied and feeling better throughout the day. It's so nice to never feel overly full.  It's like getting rid of a beast inside you that was always in charge.  Always telling you to eat, then causing issues if you eat too much or too little.  That's all gone.  I don't even have to worry about blood sugar issues if I delay eating.  That's huge for me.  I'm not diabetic, or even pre-diabetic, but I was very sensitive to low blood sugar levels for the past two decades.  I always knew that I couldn't delay eating more than an hour or two without feeling terrible.  But that's gone. 

I consider it pretty magical.  Side effects for the first week: I felt very cold.  Almost like when are getting sick.  That lasted one week.  Then, on days of injection (once per week) I would get indigestion.  After 5-6 weeks that once a week indigestion is gone.

I consider it the most effective medicine I've ever taken in my life.  I'm fortunate because I get it for $25 a month through my insurance.  I have to enroll in a program where I meet with a "coach" every 2 weeks, but the meetings are easy and short zoom calls.
Title: Re: Ozempic
Post by: tp4tissue on Sat, 14 December 2024, 13:44:12
Keep us posted PixelPusher.  Glad it's working out for you.

Heard some crazy side effect stories where this one woman's bowels stop moving completely even after stopping the drug. She can't poot, it doesn't move.   :-X
Title: Re: Ozempic
Post by: Jugizafupe on Wed, 11 February 2026, 20:31:38
The appetite suppression is definitely intense, but the long-term metabolic impact is what worries me. There are already a lot of legal inquiries happening because people weren't fully warned about the risks. I saw some information through Oberheiden P.C. (https://federal-lawyer.com/injury-lawsuit/) about how these drugs are being classified in recent misconduct cases. It's definitely not just a simple "cure" without consequences.
Title: Re: Ozempic
Post by: pixelpusher on Wed, 11 February 2026, 21:24:07
Quote from: tp4tissue on Sat, 14 December 2024, 13:44:12
Keep us posted PixelPusher.  Glad it's working out for you.

Heard some crazy side effect stories where this one woman's bowels stop moving completely even after stopping the drug. She can't poot, it doesn't move.   :-X

All good here.  Been on GLP-1 for 16 months.  I’m on a pretty low dose.  Once a week injection.  It costs me $25 per month.  I lost 65 pounds in less than a year and haven’t lost weight in about half a year now. 
I settled at exactly the same weight I was in my senior year of high school.  I used to go to the gym in high school to try to put on muscle (I was a vegetarian and was eating 5 meals a day) but I never could gain a pound.  That weight is exactly what I currently weigh at age 49.  Interesting, right?
No notable side effects for me. 

The biggest thing is that it helps me to not eat out of boredom or need for emotional comfort. 
Title: Re: Ozempic
Post by: fohat.digs on Thu, 12 February 2026, 08:03:51
Quote from: pixelpusher on Wed, 11 February 2026, 21:24:07

No notable side effects for me. 


Do you see this as a long-term thing? I would love to knock off 20 pounds, but don't want to get into something that will never end.