I think ergonomics need to be carefully looked at. Fatigue style pain is more associated with needing less force in a switch, feels different than just having wrist pain after an hour. This sounds a little more like Fanmonty needs to carefully examine ergonomics and form. I get wrist pain sometimes doing the reach, because of full size keyboard versus trackball location. I do get mild fatigue if I have a major document to type up on the rubber chicklet, because it requires more force, than my cherry brown board. Fatigue pain feels quite different than that bad ergonomically caused pain and more importantly fatigue can be felt and one can take a break, then jump back in, before any pain happens. Fanmonty do you feel the pain of exercising muscles you aren't used to exercising? Do you have someone that can watch you and see where you went wrong ergonomically? Can/have you catch yourself bending your wrists in ways you shouldn't? If you take a moment and train a friend what to watch for, even a non professional can spot some basics.
Makes me happy that I hover (laptop being the only exception) and don't have to bother buying wrist rests. I do like having wrist rest for the mouse, occasionally.
If it is fatigue, then it sounds like Fanmonty needs browns or reds or blues, but clearly the OP likes backlit, which without modding good luck on that. I really want a blue or multicolor LED backlit board with reds for gaming, myself. Unless I'd made the plan to mod before purchase, then I would return a $169+ board, rather than switch out the springs on all the switches, too. I think I can actually handle the extra force of blacks and clears, but it still wouldn't be my daily driver.