wall of text - not trying to piss off the orbweaver users. this is just my opinion on a possible layout.
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The orbweaver does have enough keys for most FPS games though, at least the ones where you actually need time and precision. If you're playing something like CS then the only thing you might want on another layer is buy macros. After I got mine I have been using it with great success in CS games and TF2, so I'd be interested to know what kind of precision fps games you play that requires more keys than the orbweaver has.
I play cs also.
After looking further at this you can do it. It is just really not optimal.
The orbweaver has a 5 x 4 layout. plus the thumb button for jump. or use your mouse wheel to jump.
lets say this is your layout ....
rifle(1), pistol(2), knife(3), nademenu(4), bomb(5)
scoreboard(Tab), quickswitch(q), forward(w), use(e), reload(r)
Walk(shift), strleft(a), back(s), strright(d), drop(g)
Duck(CTRL), stdradio(z), groupradio(x), reportradio(c), buy(b)
This leaves you with no dedicated buttons for flash, nade, smoke, moltov(cs:go), decoy(cs:go), say, team say, team switch, voice comm, esc/tilde
flash, nade, smoke:
This is the part that bugs me when I watch other people play and it really divides the community.
switching directly to a nade of a specific type can really mean a lot.
A lot of players rebind 6-9 to be 4,T,G,V or something similar.
If you can get to the specific nade you actually need you will not get caught as much with a nade in your hand because you took to long to find the one you actually need.
say,teamsay.... doesn't matter you can't really type in this layout.
teamswitch: you might as well also use your other keyboard.
Voice Comm: how do you talk to your team?
buying: you can not fully buy with the keyboard because you only have 1-5 bound. I guess you could buy with your mouse :|
stdradio, groupradio, reportradio: You could choose to not use them, but they are very powerful if used correctly.
Esc/Tilde: How do you cancel the buy menu without esc?
please tell me you use fast weapon switching?
Pressing 2 keys at once doesn't take longer than pressing a single key alone tho...
Problem is burning it into your muscle memory and doing it as reflex, can take very long.
Sure, if implemented in a way that won't work against you mid fight like moving out of the wasd position.
edit: all edits were grammar/typos. I am sure I missed some.