Topre keyboards maybe are nice to type with but are incompatible with Cherry MX.
With Cherry MX one can easily interchange the switches by using basic tools if the switches are PCB mounted. Plate mounted Cherry MX would require rework without a doubt for starters. That said, if there are any issues with Cherry MX boards, it is possible to replace the affected switches as needed. Unlike Topre where if it fails, it would probably be because the board is defective, depending on what sort of damage (if any) it could result in costly repair. However, at the same time there has been no reports of defective or troublesome Topre boards apart from rubber dome hardening (to a small amount) to my knowledge.
Gaming on either boards heavily depends on one's perception. Personally because I have HHKB Pro (and these are Topre based) I try to not game with them because of the price that I had to fork out for mine. Topre boards in general may not cost as much but I guess the sense of paying for something a little exotic, it tends to be that gaming on them for instance puts ridiculous amounts of wear on certain rubber bits imo. If I were to seriously game, I would try to game with other keyboard switches (like for instance Cherry MX) where they are dime a dozen in general (compared to Topre as mine had to be imported). Also again, if say the rubber domes on my Topre starts to stiffen, I cannot simply go out and buy the rubber pads alone. I basically have to buy an entire keyboard just to source the items and put it onto my HHKB. Unlike Cherry MX for instance where the switch, housing and all comes in a nifty "package".
Of course in no way shape or form am against Topre and/or if it were to be used for gaming. I am sort of basically implying unless if one is rich, using Topre boards for gaming for instance seems to also be a bit of a waste. I am sure if in theory I were to game with my HHKB Pro it would be fun as the keys feels nice and soft (compared to my old but cheap membrane keyboard) but again it raises flags in my eyes over the price I had to pay for mine and a few other factors (such as no factory warranty and what happens if something goes wrong with my expensive keyboard) seems to inhibit my willingness.
A fair few people here have tried Topre (on this forum) and have somewhat preferred typing on Topre instead. You can probably imagine the feeling if owning a Topre board, it feels rather nice to type on and all for the price that you pay for it. Cherry MX does also have areas where they shine, notably in other areas such as customisability (Topre has quite little in fact). Though at the end of the day, they are almost two very different fish altogether.