I think the problem is that the computer locks out the ability to shut off the engine in those vehicles while at speed...remember hearing someone mention that. From what I've seen of the very recent Prius-highway-California-whatever incident it took many repeated attempts to shut off the engine before the car responded.
To be specific, in Toyotas with a push-button ignition, you have to hold the button for 3.3 seconds before it will respond. Just like ATX, but people may not know that.
With a key ignition, I don't believe there's a single car that allows the ECU to still receive power with the key anywhere but on or start. And, on EFI, removing power from the ECU kills the PWM signal to the fuel injectors (meaning they don't fire) as well as the signals to the coils, meaning they don't fire, so you don't get fuel or spark. Need compressed air, fuel, and spark for a gasoline engine to run, take away either of them, and things stop.
However, the reason for not allowing the push-button ignition to shut off the car with just a tap, ironically, was to prevent lawsuits. They didn't want someone to accidentally bump the button, causing engine power to go away when the driver least expected it.
Similarly, the transmission cannot be geared down forcefully by pushing it into one of the low ranges because the computer locks out that functionality once you're past a safe RPM and speed for that range (this is true for all modern vehicles with electronically controlled automatic transmissions, so just about everything made after 1995 and many vehicles prior as well).
Toyota designed the safest car in the world, if you happen to be the engine. You'll never be allowed to rev too high.
And on Toyotas, they don't even allow entering neutral with over 50% throttle, to prevent an overrev that the ECU can't react to in time.
Myself, I'll just stick to my car with key ignition and a manual transmission.