I'd be surprised if the media keys and all of the other various shortcuts worked out of the box on a Mac with a WASD keyboard, either. I've had to use Karabiner Elements on every Windows keyboard I used on a Mac if I wanted the F keys to work as all of a Mac's various shortcuts. I used a Filco on a Mac for quite a while using that program, and also had a couple of Cherry boards, and now a Topre. If you don't want the F keys to be Mac-like, then you just swap the keys in System Preferences, as Mode noted.
All that aside, I think the two keyboards are pretty much a toss-up. The WASD doesn't have its lock lights labeled, which bugs me, but does give it a stealthier look. I kind of like the Filco logo, but the center-exit cable on the Filco keyboard is slightly annoying.