Doubt it, I currently have two mice plugged in that should both be set to 1000hz, and it's not giving me any issues. The only issue I can think of is that you might not get 1000hz on both mice, but from what I've read you rarely get that anyways.
Also, to those who know more about this than me; is there really any point of having your polling rate higher than your monitors refresh rate? If you have a 120hz monitor will a 1000hz polling rate really be different from 500hz?