Welcome to geekhack!
Sometimes the Escape key on a 60% board is setup as a dual use key so if you're using the standard firmware it could be that. Download
Aqua Key Test and press ctrl+shift+esc to see what the computer sees you pressing.
It's possible that backspace has similarly been remapped when you hold ctrl, or it could be due to number lock being on on one computer but not the other and a virtual numberpad setting... Again, Aqua Key Test will reveal what keys you're pressing.
Assuming this finds strangeness it's just a matter of flashing firmware that does what you want. Feel free to post what keys you see and a pic of your board if you need help with that
