I have one of these at work:
CleanKeys
I got it as the lowest-force alternative to my Datahand while unable to use my left hand for typing after surgery - as the typing surface is a solid sheet of glass, with a capacitive touch surface on the underside, you can actually type without touching the surface at all! (you can actuate it from 3-4mm away on the highest sensitivity setting).
Obviously it's easy to clean as there's nowhere for dirt to hide - hitting Fn+Pause suspends operation so you can wipe it without generating spurious keypresses. It has a nice feedback 'click' noise (3 volume settings, or off) which helps a lot with the lack of tactile sensation. You can set the sensitivity as low/med/high as well.
I definitely wouldn't use it for gaming as the rollover is very strange - it seems to be divided into two portions left and right, and can register only one of those sides at a time, but it can do this with any combination of ctrl, alt, win, lshift, rshift or altgr. Weird! It also doesn't have a windows-style 'right-click' key, if that bothers you.
I've found the layout to be OK - it's close enough to UK standard that it's easy enough to switch to, the main issue being the arrow keys which still catch me out after a couple of weeks using it. The trackpad is nothing special - you can tap-click but not scroll (apparently there's a firmware fix for this but I haven't got it yet) but fine for medium-duty office use, it's just a standard pad. The glass is frosted above the pad surface which gives it a nice tactile feel - it can be quite easy to drift off it and hit 'return' by mistake though.
It's advertised as washable but not proof against immersion - I get the impression you could run it under a tap and even immerse it for short periods without trouble. The base is made of Corian (as in the artificial ceramic material used for kitchen surfaces) which makes the whole thing very solid - it definitely won't move around on the desk. As the Corian and glass are bonded with epoxy and there's a silicon bead between the two it should survive spills easily - the weakest point is the cable exit, which has a soft rubber strain relief to give extra protection.
The biggest downside is the price - they're £351 each. If you can convince work to buy you one they're really good for rehabilitation due to the very very low activation force - but I guess you'd have to be a real cleaning freak to get one just because you can wipe it down. Then again maybe you have a very messy desk ;-)
Stone