I realize the foam is a non-issue...was just joking being Ripster used to mention the foam all the time.
I've never had any issues with my AT board and the computers I use. All my desktop computers at the office work with it via the PS/2 port, and all my notebooks work with it using a Blue Cube. It might be an issue for certain people, but I doubt for very many.
The layout would definitely be a problem for some people. I personally don't need Windows keys nor F11/F12. But I would prefer my F keys to be up top, not on the left. But everyone's different with what is their ideal layout, and what is an acceptable layout.