Subjectivity is overrated. Get a book or two on design principles and read up. There are rules and standards of good design that don't just hinge on personal sense of taste, one of these being orange/blue or similar color contrasts being pleasing to the eye.
If you're looking for something distinctive, don't just smash some Internet memes here and there and expect people to fall at your feet. Don't focus too much on individual keycaps either, but an overall look.
Try using a font that hasn't been used widely in new keycaps, or distinctive color patterns based on each row, or even better, a cross or diagonal pattern of colors. The market is saturated with desaturated-looking "gamer" equipment; use RYB secondary colors (orange, green, violet) for a look you don't often see. If money or effort's no object, try going for a wooden case, maybe a well-polished walnut or mahogany.
If you want to be noticed, you have to do things other people don't do, which involves going to lengths in effort and planning that other people normally don't. You have a vague idea at this point, from what I've seen in your posts; try to focus on a specific theme or style. Preferrably not 8-bit, because that's horribly overexposed, and it doesn't work so well with off-centered "pixels" like keys on keyboards.
