I've been staring at my screen much more than usual lately (mostly MS Word and reading journal articles), and developed a 'nervous twitch' on my right upper eyelid. My LCD brightness is around 25 (Dell U2711), and I lower it even more at night. The top of my screen is about 1" above my eyes.
I decided to try the Gunnar optics. I'd read a couple reviews that seemed positive, and more than a few that were negative or just made fun of the idea, but after four straight days of eye twitching I was ready to spend $100 to find out.
Long story short, after about five minutes wearing these I found them VERY annoying, like when you wear someone else's prescription glasses. I didn't mind the slight yellow cast, and the contrast of text definitely appeared better. The glasses sit such that the bottom of the frame partially blocks my view of the keyboard, meaning I have to move my neck if I need to see the keys.
They're going back.