The surfaces need to be very clean, but I would avoid sanding if possible. Anything rough enough to leave a texture will probably chew up more skin, and anything smooth will not match.
Something that I have done - and this is very touchy - is spray on a relatively heavy coat, wait until it is just tacky, and lay a paper towel lightly onto the area in question for just a second, then gently pick it back up. If you did it right, it will raise little tiny peaks which will then dry.
Then, later, another coat or two over that might - if you are lucky - blend it all back to a similar texture.