Ah, of course, since it's per user. So is your search for something else basically motivated by it being a hassle to change the settings?
I haven't tried this yet, but if the shortcut key was enabled, I'm wondering if it would trash the 'fast' values. You could try that by setting the Flags entry to 63 instead of 59.
Anyway, I couldn't find a utility that was able to set the 'fast' values, so I started writing one
I've found that it's optional to write the settings to the registry at all... there's a 'current' set, which presumably wouldn't be saved across a log-off-on. Might be useful when just running a game that works better with it on.