I know that
whatchamccallum put a Logitech trackball into his Kinesis contoured. The images from the
thread are gone, so I'll repost the one I have saved:
That Kinesis model has empty space inside the front, centre, with a separate PCB for each thumb cluster. There are also Kinesis keyboards where the thumb clusters and the controller are on a single PCB in the front, where in you can not do this mod.
Other people have mod'ed their Kinesis with trackpads in that position. There are Maltron models that come with a trackball in about the same position. Acer Future Keyboard is a split and tented QWERTY board with a trackpad splitting the space bar. There are also a couple models of TRON keyboards (split, tented, column-oriented but not contoured), that have a small pen tablet in front of the thumb keys.