Theoretically I would think that it'd be worse by design, because with fingers on the home row, they either move up or down, but never more than one row. If they were on the top row, they would move down one or two rows, which I imagine would be straining if you reached for a key like '?', 'Z' or pretty much any bottom row key. I personally like a position with three on the top row, and index fingers on the middle, but I type Dvorak so that might be less applicable.