I had carpal tunnel syndrome in both wrists and the only solution was surgery. I went to a hand-surgery specialist and the results were 100% free from pain. I tried various remedies, different keyboards, and naturopathy prior to surgery, none of which worked. Some people get a cortisone injection, which reduces swelling, and never need surgery. My surgeon suggested I try it, which I did, but my pain returned two months after the injection. I know the question wasn't whether or not one should undergo surgery; however, from my experience, the best thing to do is find a qualified surgeon who specializes in hand surgery and have done with it.