ugh at lay-out discussions...
Then I suppose I should apologize to you in advance, because presumably that's the sort of advice that is being sought.
My guess is that the 60% keyboard is intended to be something like this in its default state:
Given that the other keyboard is shown with the right-hand Windows Shift key being replaced by the Fn key, presumably that's what is intended for this one as well. As I've noted before, I suggest replacing the Windows Menu key by the Fn key instead.
So, in Fn-shift, the top row, going across, would be Esc, F1 - F12, and finally Windows Menu.
There are alternative choices, of course. Pause/Break is more "dangerous" than Esc, so perhaps the key in the upper left would normally be Esc, and then Fn-shifted to be Pause/Break.
Or, since Scroll Lock is very rarely used, the key in the upper left might normally be Esc, Fn-shifted to be Pause/Break, and Pause/Break would replace the key shown as Scroll Lock in the diagram.
Also, accidentally hitting Caps Lock is a common complaint. So, Caps Lock might be made into a second left-hand Fn key (and then swapped with left-hand Ctrl as well, possibly). In that case, since the key in the upper right is Num Lock, it would be easier to remember if that key were Fn-shifted into Caps Lock... and Fn-backspace were used for the Windows Menu key.
The extra key on the ANSI layout should somehow be available. If it isn't a physical key (with room made for it by shortening the right-hand shift key), I suppose the most obvious option is Fn-Tab (or even an Fn-shift of the ~` key, but I would recommend against that as confusing, when the keyboard is in a state in which none of the other printable character keys have Fn shifts).
As long as you've got an Fn key, however, I think it would be a good idea to have the option of switching the keyboard into... shall we call it Otaku mode... in which the printable character keys do have Fn shifts, such as allow you to use the keyboard without ever using the top row - presumably with the same layout as used for the product without a top row.
The numeric keypad should go in the standard laptop locations, which are visible in the image. As Fn-shift is not expected to bring up the numeric keypad, there is no conflict in using the same keys for Fn-shifts, and my personal preference for the layout of that kind of keyboard, which matches neither the MiniGuru proposal nor the HHKB, would be something like this:
-----------------------------------------------------------
| | | | | | | | | | | | | | |
|ESC|F1 |F2 |F3 |F4 |F5 |F6 |F7 |F8 |F9 |F10|F11|F12| |
|-----------------------------------------------------------|
| | | | |PG | | |CAP|WIN| < | | | | |
| | |INS|HOM|UP | | |LK |MNU| > | | | | |
|-----------------------------------------------------------|
| |NUM| | |PG | | | | | ^ | | | | |
| |LK |DEL|END|DN | | |<- | ->| | | v | | |
|-----------------------------------------------------------|
| | |PRT|SCL|PAU| | | | | | | | |
| | |SC |LK | | | | | | | | | |
|-----------------------------------------------------------|
| | | | | | | | |
| | | | | | | | |
-----------------------------------------------------------
The Fn-shifts for the cursor keys are directly on the home-row positions of the right hand. (Which makes a left-hand Fn key important.)
The keys from Insert to Page Down are laid out exactly as on the standard keyboard, making them easy to find, and they're either on the home row, or up-reaches. The more difficult down-reaches are reserved for the less common Print Screen to Pause/Break keys, again in their standard relationship.
These keys are in columns 2, 3, and 4, not 1, 2, and 3, so that the little finger instead of the index finger is the one not used.
The <> key represents the extra ISO-layout printable character key; perhaps Fn-~` would be better than Fn-O for that key (but right now, that position is used for Esc, as being the easiest to remember).
Also, note that cursor left and cursor right are the Fn-shifts of J and K, so that they're under the two strongest fingers, although that is not the same arrangement as that of the cursor keys in the top row, which puts cursor left and cursor right on the right, so that cursor left is closer to backspace.