Cherry profile is lower, so the keycaps aren't as tall. It doesn't really take much getting used to, as the slope is similar, but I find that OEM profile makes switches easier to actuate--less effort. I still overall prefer Cherry profile in thick PBT keycaps.
If you're going to be replacing all keycaps for a full new set, it doesn't matter which one you pick--both should be fine for WASD and Filco. It's when you mix and match Cherry profile and OEM profile, there will be height/slope difference that might be awkward and won't look good.
(And yes, they come with "OEM" profile keycaps by default).