My first response was that this seems overly cumbersome and unnecessary.
Then I realized that people who can't use a keyboard at all (or at least, well enough for for one to be useful) due to disabilities will be very grateful for this board's existence. Sadly, I have a suspicion it will be expensive... thus it will likely be out of reach of most of its target audience's price range.
And if you're a gamer who plays anything other than Pogo games and Bejeweled clones, this definitely won't work for you.