@tp4tissue, many wrist supports (including rollerblade wrist protectors from a quick Google) have a piece that goes under the wrist and up to the palm. This is usually metal and doesn't flex, which isn't comfortable for long periods. It stabilizes the wrist for when you have an injury, but for computing I think it is more important to keep the wrist straight with the top of the arm. For this you need a support piece on top of the wrist, but it can't be too rigid. Also I have found the palm support pushes away the mouse (back when I used a mouse).
@SonOfSonOfSpock, the M570 looks like it requires your palm to rest on it, so I can see the glove's bean bag being a problem. You could try massacring the glove to remove the beads, but I'm afraid you'd be left with too much material at the palm.
I could do without the beads most of the time, though they help a little if I rest my hands on the keyboard. I really like the Expert Mouse trackball with its integrated scroll wheel, but it's a bit spendy. The gloves will loosen up over time, but you would probably find the thumb support version more comfortable. I tried the Imak Computer Glove but wasn't impressed. It is smaller and doesn't have the splint above the wrist, which IMO is key.
@hoggy, aye, I a couple days ago I looked down at my Microsoft Comfort Curve 3000 keyboard and saw it was caked with dog hair. I remove the spacebar and vacuumed it, but couldn't get all the nasty out without removing all the keys. After putting the spacebar back on I found it wobbled without being pressed about half an inch, which wasn't fixable by adjusting the stabilizer. Off I went, Googling keyboards and after about 12 hours of research I decided on the Realforce 87U EK.
I'm really excited about it, not just how the Topre switches will feel, but not having a stupid tenkey pad will put my trackball much closer. I think will make using the computer more comfortable, less asymmetrical reaching and faster mouse/keyboard transitions.
The Kinesis looks interesting. I'm afraid I could never get used to it though. I started computers at 11 and I'm a self taught typist, which is basically to say I'm a super fast hunt-and-pecker.
I touch type, but not in the proper/traditional way, and it is quite ingrained after 22 years of doing it wrong. I haven't been able to get used to a split keyboard, even though it seems much better.