I've been using a Wacom Pen and Touch for nearly ten years and never want to go back to a mouse!
I'm a software developer and used be a hardcore gamer (started playing CS in the beta era and played it non-stop), but I started developing several issues with my right arm and hand.
The first thing I did was started using my left hand and long story short; just don't do it.
Then I started looking into mouse replacements.
The fist thing I bought was a HandShoeMouse which looked promising at first but has lots of design flaws and actually made most of my problems worse.
http://handshoemouse.com/Then I bought a Logitech rollerbal mouse which relieved most of the issues but my left thumb was still hurting and that's the main thing you use on that device.
It still has a purpose though, its ideal for using in a data center and stuff.
Finally I purchased a Wacom Pen and Touch and after a few hours of getting the settings just right I was already in love with it.
Moving the cursor is just moving the pen hovering over the surface and clicking is just tapping the pen on the surface.
And you scroll just like you would on any other touch surface
The movement feels just as natural as with a normal mouse.
Here is a picture of my Wacom:
https://geekhack.org/index.php?topic=90470.0;To clarify, these are my issues whenever I use a regular mouse for longer than 15 minutes:
- Bear arm, when the input device is to much to the right
- Index finger hurts at the knuckle from clicking
- Thumb hurts at the knuckle from gripping the mouse
- Wrist hurts because of no tenting
In my opinion its the only good mouse replacement by a mile (I haven't tried a rollerbar mouse though).
It's the only device I've found so far that doesn't trigger any of my issues and keeps me having a job...
Hope this helps!