Well, it is usually in the design of the amplifier, so the user does not really have a lot of choices here. I usually also use balanced audio for everything. In fact, I once made an error in the PSU design, resulting in more of a noise generator than a PSU, it was very loud with single-ended,
but not even measurable (or audible) on the balanced output. It does however also require the design to be properly balanced and not introduce any common mode noise earlier in the processing chain.